Cross-protective Vaccine May Treat Broad Spectrum Of Bacterial Diseases (October 23, 2008) -- Doctors have always hoped that scientists might one day create a vaccination that would treat a broad spectrum of maladies. They could only imagine that there might be one vaccine that would protect against, say, 2,500 strains of Salmonella. And what if that same vaccine could help protect the elderly? ... > full story
Chronic Inflammation Can Help Nurture Skin Cancer, Study Shows (October 23, 2008) -- Inflammation, a frontline defense against infection or disease, can help nurture skin cancer, researchers have found. IDO, an enzyme that works like a firefighter to keep inflammation under control, can be commandeered to protect early malignant cells, say researchers studying an animal model of chronic inflammation and skin cancer. ... > full story
New TB Test Reveals Patients At Risk, Says Study (October 23, 2008) -- A recently introduced blood test can reveal which patients may develop active tuberculosis much more precisely than the 100-year old TB skin test, according to a new study published today in the journal Annals of Internal Medicine. Around a third of the world's population is infected with the TB bacteria and approximately 9 million new cases of active TB are diagnosed around the world each year, according to World Health Organization estimates. The majority of those infected live in the developing world. ... > full story
Different Psychosocial Factors Predict Adoption, Maintenance Of Physical Activity Program (October 23, 2008) -- A new study offers some new insight into the role of social and environmental influences on physical activity behaviors. ... > full story
Safety Problems For Biological Products Documented (October 23, 2008) -- Approximately one in four biological medicinal products (such as antibodies, enzymes and insulin) approved since 1995 in the US and Europe have had at least one safety-related regulatory action issued for them 10 years after their approval, including about 11 percent receiving a "black box" warning, according to a new study. ... > full story
Biomarkers For Identifying Infant Infections (October 23, 2008) -- Current diagnostic tests for infection in premature infants can be slow and nonspecific, but researchers have now identified potential biomarkers in the blood that can rapidly identify both the onset of infection and type of microbe. ... > full story
Chest Scans May Help Monitor Spread Of Head And Neck Cancer In High-risk Patients (October 23, 2008) -- Among high-risk patients with head and neck cancer, chest computed tomography may help detect disease progression involving the lungs, according to a new report. ... > full story
Hospital Rankings: More Than Meets The Eye (October 23, 2008) -- Medicare's pay-for-performance program ranks and rewards hospitals according to how well they meet certain guidelines for clinical care. But researchers say the program penalizes hospitals that care for the greatest numbers of the poor and needy by not taking into account their greater clinical burden. ... > full story
Crossing Blood-Brain Barrier: Scientists Develop Drug Delivery System For Brain Cancers, Other Diseases (October 22, 2008) -- Scientists have developed a new drug delivery system that is capable of crossing the blood-brain barrier to reach and kill cancer cells in the brain. Following successful preclinical studies, the technology is being evaluated in two phase I clinical trials in patients with malignant glioma and brain metastases. ... > full story
Common Respiratory Syncytial Virus May Hide In The Lungs, Lead To Asthma, Researchers Report (October 22, 2008) -- Conventional wisdom has been that respiratory syncytial virus -- a common virus that causes infection in the lungs -- comes and goes in children without any long lasting impact. A study conducted in mice, however, suggests that RSV may hide in the lungs even after other symptoms abate, ultimately resurfacing to cause recurrent wheezing and chronic airway disease. ... > full story
Estimate Of Lives Lost Due To Delay In Antiretroviral Drug Use For HIV/AIDS In South Africa (October 22, 2008) -- More than 330,000 lives were lost to HIV/AIDS in South Africa from 2000 and 2005 because a feasible and timely antiretroviral (ARV) treatment program was not implemented, assert researchers in the Journal of Acquired Immune Deficiency Syndromes. ... > full story
U.S. Suicide Rate Increasing; Largest Increase Seen In Middle-aged White Women (October 22, 2008) -- The rate of suicide in the United States is increasing for the first time in a decade, according to a new report. The increase in the overall suicide rate between 1999 and 2005 was due primarily to an increase in suicides among whites aged 40-64, with white middle-aged women experiencing the largest annual increase. ... > full story
Erectile Dysfunction Gives Early Warning Of A Heart Attack, Warns Expert (October 22, 2008) -- Erectile dysfunction gives a two to three year early warning of a heart attack, warns an expert. ... > full story
New MRI Technique May Identify Cervical Cancer Early (October 22, 2008) -- Using high-resolution magnetic resonance imaging with a special vaginal coil, a technique to measure the movement of water within tissue, researchers may be able to identify cervical cancer in its early stages, according to a new study. ... > full story
Computer Model Against Unnecessary Use Of Antibiotics (October 22, 2008) -- Patients in intensive care units are often administered antibiotics against ventilator-associated pneumonia, "to be on the safe side." Researchers have now developed a model that can quickly establish whether or not a patient has pneumonia. This can prevent unnecessary treatment with antibiotics. ... > full story
Couples With Children With ADHD At Risk Of Higher Divorce Rates, Shorter Marriages (October 22, 2008) -- Parents of a child with attention deficit hyperactivity disorder are nearly twice as likely to divorce by the time the child is 8 years old than parents of children without ADHD, the first study to look at this issue in depth has shown. ... > full story
Scientists Enhance Immune System Attacks On Cancer (October 22, 2008) -- Researchers have tweaked, prodded, and pushed immune system cells into successfully attacking tumors in laboratory and animal studies. They say their new strategy could prove to be safer than some treatments now being used to stimulate cancer immunity in humans. ... > full story
X Marks The Spot: Sharpies Get Thumbs-up For Marking Surgery Sites (October 22, 2008) -- Researchers have found that Sharpies used to mark surgical sites do not pose a risk of bacterial infection since the ink has an alcohol base. It's standard practice to throw away marking pens used to mark operative sites after one use to prevent the spread of germs, costing thousands of dollars a year. ... > full story
Evolution Of Genes That Trigger The Body's Immune Response To Viral Infection (October 22, 2008) -- Researchers have traced the evolutionary origin of two genes that serve as primary cellular sensors of infection with RNA viruses, such as influenza, polio virus, West Nile virus, and HIV, which may ultimately provide researchers with insight into a possible new pathway for the development of innate immunity. ... > full story
Eating Quickly And Until Full Triples Risk Of Being Overweight (October 22, 2008) -- The combination of eating quickly and eating until full triples the risk of being overweight, according to a new study. ... > full story
Contact Lenses Are Home To Pathogenic Amoebae (October 22, 2008) -- Contact lenses increase the risk of infection with pathogenic protozoa that can cause blindness. New research shows that a high percentage of contact lens cases in Tenerife are contaminated with Acanthamoeba that cannot be killed by normal contact lens solution. ... > full story
Allergy Patch Test: Children Tend To React To Different Allergens Than Adults (October 22, 2008) -- Adults and children who are referred for patch testing of allergens appear equally likely to have allergic contact dermatitis, although they tend to react to different allergens, according to a new report. ... > full story
Scientific Hunch Poised To Save Thousands From Toxic Fish Poisoning (October 22, 2008) -- A neuroscientist has found a way to combat a debilitating illness that affects an estimated 50,000 people a year in tropical regions. ... > full story
Education Protects Against Pre-Alzheimer's Memory Loss (October 22, 2008) -- People with more education and more mentally demanding occupations may have protection against the memory loss that precedes Alzheimer's disease, according to a study in Neurology. ... > full story
Tick-borne Encephalitis Virus Reveals Its Access Code (October 22, 2008) -- Biologists have identified an amino acid switch that flaviviruses flip to gain access to cells. Flaviviruses such as tick-borne encephalitis virus (TBEV), yellow fever, and dengue are dangerous human pathogens. ... > full story
Egg-beater Could Save Lives In Developing Countries (October 22, 2008) -- Plastic tubing taped to a handheld egg-beater could save lives in developing countries. The low-cost centrifuge replacement can separate plasma from blood in minutes, which is used in tests to detect lethal infectious diseases responsible for half of all deaths in developing countries. ... > full story
'Western' Diet Increases Heart Attack Risk Globally (October 22, 2008) -- A study that examined various dietary patterns suggests that the typical Western diet -- fried foods, salty snacks and meat -- accounts for about 30 percent of heart attack risk across the globe. A diet high in fruits and vegetables was associated with a lower risk of heart attack. A diet high in tofu and soy did not affect heart attack risk. ... > full story
Self-assembling Nano-fiber Gel Delivers High Concentrations Of Clinically Approved Drugs (October 22, 2008) -- Scientists have developed a new self-assembling hydrogel drug delivery system that is biocompatible, efficient at drug release, and easy to tailor. Importantly, these structures can deliver clinically approved drugs in high concentrations without requiring carriers for the drug or generating toxic components, a problem with hydrogel systems until now. ... > full story
Mechanical Pressure Accelerates Early Stages Of Colon Cancer (October 22, 2008) -- Genes are not the be all and end all of carcinogenesis. Scientists have shown that mechanical pressure can alter gene expression, and in particular activate the oncogenes(1) Myc and Twist, which are implicated in the early stages of colon cancer. ... > full story
T Cell Response To New Melanoma Antigen Linked To Relapse-free Survival (October 22, 2008) -- Melanoma patients infused with a special type of tumor-fighting T cell are more likely to survive without relapse, suggests a new study by researchers in France. ... > full story
Grades In College Directly Linked To Health-related Behaviors (October 22, 2008) -- Lack of sleep, excessive television/computer screen time, stress, gambling, alcohol and tobacco use and other health-related issues are taking a toll on college students' academic performance. ... > full story
On The Trail Of A Targeted Therapy For Blood Cancers (October 22, 2008) -- Researchers are examining a family of blood proteins that they hope holds a key to decreasing the toxic effects of chemotherapy in children and adults. Their findings may one day help in the development of targeted therapies for leukemia, multiple myeloma and other cancers of the blood. ... > full story
How Neuronal Activity Leads To Alzheimer's Protein Cleavage (October 22, 2008) -- Amyloid precursor protein, whose cleavage product, amyloid-b, builds up into fibrous plaques in the brains of Alzheimer's disease patients, jumps from one specialized membrane microdomain to another to be cleaved, according to a new report in the Journal of Cell Biology. ... > full story
Out Of Mesopotamia: Evolutionary History Of Tuberculosis (October 22, 2008) -- The evolutionary timing and spread of the Mycobacterium tuberculosis complex (MTBC), one of the most successful groups of bacterial pathogens, remains largely unknown. Using mycobacterial tandem repeat sequences as genetic markers, scientists show that the MTBC consists of two independent clades, one composed exclusively of M. tuberculosis lineages from humans and the other composed of both animal and human isolates. ... > full story
Creating Unique Health ID Numbers Would Improve Health Care Quality, Efficiency, Study Claims (October 22, 2008) -- Creating a unique patient identification number for every person in the United States would facilitate a reduction in medical errors, simplify the use of electronic medical records, increase overall efficiency and help protect patient privacy, according to a new study. Although the cost of such a system could reach billion, the effort would likely return even more in benefits to the nation's health care system. ... > full story
Can Exercise Prevent A Severe Stroke? (October 22, 2008) -- A new study shows that people who are physically active before suffering a stroke may have less severe problems as a result and recover better compared to those who did not exercise before having a stroke. The research is published in the journal Neurology. ... > full story
Pandemic Flu Models Help Determine Food Distribution And School Closing Strategies (October 22, 2008) -- Pandemic flu models can help organizations improve their food distribution and school closing strategies in the event of such an emergency. The models are flexible so that multiple scenarios can be investigated to see which options meet an organization's specific goal. ... > full story
Embolic Neuroprotection System Reduces Risk Of Cardiac Events, Study Reveals (October 22, 2008) -- New research shows a low number of strokes and cardiac events in patients who had stents implanted utilizing a new embolic neuroprotection system during carotid stenting with commercial stents. ... > full story
Vaccine Type That Holds Promise In Protecting Against TB Identified (October 21, 2008) -- A recombinant vaccine against tuberculosis shows promise, researchers find. The investigational vaccine for TB appears likely to offer significantly better protection against the potentially fatal disease than the one in current use. ... > full story
Potential New Way To Make A Good Anti-leukemia Drug Even Better (October 21, 2008) -- A recently identified cancer-causing protein makes the anti-leukemia drug imatinib, less effective. By blocking the protein, researchers were able to slow the spread of leukemia cells in culture. The study, which will appear in the Journal of Experimental Medicine, suggests that the most effective treatment for leukemia may rely on a combination of targeted drugs, rather than a single miracle drug. ... > full story
Effect Of Gamma Waves On Cognitive And Language Skills In Children (October 21, 2008) -- Gamma wave activity in the brains of children provide a window into their cognitive development, and could open the way for more effective intervention for those likely to experience language problems. ... > full story
Beta-blocker Use Linked To Risks Of Death And Heart Attack After Surgery, Study Suggests (October 21, 2008) -- Some patients who received beta-blockers before and around the time of undergoing non-cardiac surgery appear to have higher rates of heart attack and death within 30 days of their surgery, according to a new report. ... > full story
Non-AIDS Deaths In People With HIV Linked To Inflammation And Coagulation, Study Suggests (October 21, 2008) -- In an analysis of deaths occurring during a large international trial of treatments for HIV-positive patients, researchers have found a strong association between markers of inflammation and coagulation and increased risk of death from non-AIDS diseases, including cardiovascular problems. ... > full story
The Nose Knows: Two Fixation Points Needed For Face Recognition (October 21, 2008) -- Many of us are bad at remembering names but we are very quick to point out that at least we never forget a face. Never mind recognizing a familiar face -- how is it that we recognize faces at all? ... > full story
Man's Best Friend Recruited In Hunt For Disease Genes (October 21, 2008) -- For centuries man has had a uniquely close relationship with dogs -- as a working animal, for security and, perhaps most importantly, for companionship. Now, dogs are taking on a new role -- they are helping in the hunt for genetic mutations that lead to diseases in humans. ... > full story
Low-carb Diets Alter Glucose Formation By The Liver (October 21, 2008) -- A new study shows that a low-carbohydrate diet changes hepatic energy metabolism. When carbohydrates are restricted, the liver relies more on substances like lactate and amino acids to form glucose, instead of glycerol. ... > full story
Respiratory Rhythms Can Help Predict Insomnia (October 21, 2008) -- The breathing and heart rates and cortisol levels of women with metastatic breast cancer can be used to predict if they'll suffer from chronic insomnia and sleep disruptions, a common complaint from patients who want to maintain their quality of life, according to a new study. ... > full story
Group Bragging Betrays Insecurity, Study Shows (October 21, 2008) -- Groups that boast, gloat and denigrate outsiders tend to be of low social status or vulnerable to threats from other groups, research shows. ... > full story
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